I-epidermal structural kunye notshintsho lwe-biochemical ekugugeni kwesikhumba

I-metabolism ye-epidermis kukuba i-basal keratinocytes ihambela phezulu kunye nokwahlukana kweeseli, kwaye ekugqibeleni ife ukuze yenze i-non-nucleated stratum corneum, ize iwele. Ngokuqhelekileyo kukholelwa ukuba ngokunyuka kweminyaka yobudala, i-basal layer kunye ne-spinous layer iphazamisekile, i-junction ye-epidermis kunye ne-dermis iba yincinci, kwaye ubukhulu be-epidermis buyancipha. Njengomqobo wangaphandle womzimba womntu, i-epidermis idibana ngokuthe ngqo kunye nemeko yangaphandle kwaye ichaphazeleka ngokulula kwizinto ezahlukeneyo zangaphandle. Ukuguga kwe-epidermal kubonakalisa ngokulula impembelelo yobudala kunye nezinto zangaphandle ekugugeni komntu.

Kwi-epidermis yolusu olugugayo, ukuhluka kobukhulu, i-morphology kunye neempawu zokungcolisa iiseli ze-basal layer ziyanda, ukuhlangana kwe-epidermis kunye ne-dermis ngokuthe ngcembe kuba sicaba, isikhonkwane se-epidermal siba nzulu, kwaye ubukhulu be-epidermis buyancipha. Ubukhulu be-epidermal buyehla malunga ne-6.4% kwishumi leminyaka, kwaye behla ngokukhawuleza kwabasetyhini. Ubukhulu be-epidermal buyancipha ngokukhula. Olu tshintsho lubonakaliswa kakhulu kwiindawo ezivulekileyo, kubandakanywa iindawo ezingaphezulu zobuso, intamo, izandla kunye neengalo. Iikeratinocyte zitshintsha ukumila njengoko ulusu luguga, lusiba mfutshane kwaye lutyebe, ngelixa iikeratinocyte zisiba nkulu ngenxa yotshintsho olufutshane lwe-epidermal, ixesha lokuhlaziya i-epidermis egugayo liyakhula, umsebenzi wokwanda kweeseli ze-epidermal uyancipha, kwaye i-epidermis iba bhityile. ibhityile, ibangela ulusu ukuba luphulukane nokunwebeka nokushwabana.

Ngenxa yolu tshintsho lwe-morphological, i-epidermis-dermis junction ayiqinile kwaye isengozini kumonakalo wamandla angaphandle. Inani le-melanocytes liyancipha ngokuthe ngcembe emva kweminyaka engama-30 ubudala, amandla okwandisa ayancipha, kwaye umsebenzi we-enzymatic we-melanocytes uyancipha ngesantya se-8% -20% kwishumi leminyaka. Nangona ulusu alululanga ukuba lubentsundu, iimelanocyte zithandwa kakhulu ekuhlaleni ukuze zenze amabala ebala, ngakumbi kwiindawo ezigqatswe lilanga. Iiseli zeLangerhans nazo ziyancitshiswa, nto leyo eyenza ukuba umsebenzi wokhuselo lomzimba wehle kwaye ube sesichengeni sezifo ezosulelayo.

Isiqholisi solusuUmatshini unokusetyenziselwa ukubona imibimbi yolusu lobuso, ukuthungwa, ukulahleka kwecollagen, kunye necontour yobuso ukunceda ukubona ukuguga kobuso.