Isiphumo esiKhuselekileyo seI-Skin MicroecologykuLusu
Iingqungquthela ze-sebaceous zikhupha i-lipids, ezixutywe nge-microorganisms ukwenza ifilimu ye-lipid emulsified. Ezi filimu ze-lipid ziqulethe i-fatty acids yamahhala, eyaziwa ngokuba ziifilimu ze-asidi, ezinokuthi zithintele izinto ze-alkaline ezingcolileyo esikhumbeni kwaye zithintele iibhaktheriya zangaphandle (iibhaktheriya ezidlulayo). , i-fungi kunye nezinye ii-microorganisms ze-pathogenic zikhula, ngoko ke umsebenzi wokuqala wezityalo zesikhumba eziqhelekileyo ziyimpembelelo ebalulekileyo yokukhusela.
Ukuphazamiseka kwesikhumba kunye ne-appendages, kuquka amadlala okubila (amadlala abilayo), amadlala amdaka, kunye neefollicles zeenwele, zinezityalo zazo ezikhethekileyo. Amadlala e-sebaceous adibanisa iifollicles zeenwele ukwenza i-follicular sebaceous unit, ekhupha i-lipid substance ebizwa ngokuba yi-sebum. I-Sebum yifilimu ekhuselayo ye-hydrophobic ekhusela kwaye ithambisa ulusu kunye neenwele kwaye isebenze njengesikhuselo se-antibacterial. Amadlala sebaceous ngokwentelekiso hypoxic, ukuxhasa ukukhula facultative anaerobic ibhaktiriya ezifanaP. amaqhakuva, equkethe i-P. acnes lipase ehlisa i-sebum, i-hydrolyzes triglycerides kwi-sebum, kwaye ikhupha i-fatty acids yamahhala. Iibhaktheriya zinokubambelela kula ma-acids e-fatty amahhala, anceda ukucacisa i-colonization ye-sebaceous glands yi-P. acnes, kwaye ezi zi-acids zamahhala ziphinde zibe negalelo kwi-acidity yesikhumba (pH ye-5). Iibhaktheriya ezininzi eziqhelekileyo ze-pathogenic, ezifana ne-Staphylococcus aureus kunye ne-Streptococcus pyogenes, zithintelwe kwindawo ene-acidic kwaye ngoko zilungele ukukhula kwe-coagulase-negative staphylococci kunye ne-coryneform bacteria. Nangona kunjalo, ukuvaleka kolusu kubangela ukwanda kwe-pH eya kuthanda ukukhula kwe-S. aureus kunye ne-S. pyogenes. Ngenxa yokuba abantu bevelisa i-sebum triglycerides eninzi kunezinye izilwanyana, i-P. acnes eninzi ilawula ulusu lomntu.
Ixesha lokuposa: Jun-27-2022
