I-pigment yolusu olungaqhelekanga lwe-metabolism - chlosma

I-chlosma sisifo esiqhelekileyo sokufumana isikhumba sokufumana isikhumba kwisifo sekliniki. Kuninzi kakhulu kwabafazi bobudala bokuzala, kwaye banokubonwa kumadoda awaziwayo. Ibonakaliswa yi-shedmetrical ye-sheeks, ibunzi kunye nezihlalo, ubukhulu becala kubume bamaphiko ebhabhathane. Ukukhanya kwellow okanye i-brown emdaka, emnyama emnyama okanye emnyama emnyama.

Phantse bonke ubuhlanga kunye nohlanga olunokukhulisa eso sifo, kodwa iindawo ezinokuvezwa ngokuqinileyo, njengeLatin America, iAsia, naseAfrika, zineziganeko eziphezulu. Uninzi lwezigulana zikhulisa isifo kwi-30s kunye ne-40s, kwaye imeko yabantu abangama-40 ukuya kwangama-50 ubudala kunye ne-16%, ngokulandelelana. Abantu abanobukrelekrele abancinci bakhula kwangoko, abantu abamnyama abamnyama bakhula kamva, kwanasemva kokuyeka ukuya esikhathini. Uhlolo oluvela kubantu abancinci e-Latin Amerika ubonakalisa isimo se-4% ukuya kwi-10%, i-50% yabasetyhini abakhulelweyo kunye ne-10% kumadoda.

Ngokwendawo yokusasazwa, i-melasma inokwahlulwa kwiintlobo zeklinikhi ezi-3, kubandakanya ubuso obungaphantsi (kubandakanya ubunzi, i-dorgom yempumlo, i-zes njs, kwaye i-20%, kunye ne-15%, ngokwahlukeneyo. Ukongeza, ezinye izifo ze-idiopathic zesikhumba, ezinjenge-idiopathic ye-piopathic ye-piopathion, kucingelwa ukuba zinxulunyaniswa neMelasma. Ngokwendawo yendawo ye-melanin eluswini, i-melasma inokwahlulwa ibe yi-Epidermal, i-Demal kunye neentlobo ezixutyiweyo, phakathi kwendlela yohlobo oluqhelekileyo, kunye nohlobo oluxutywe kakhulu,Isibane somthiiluncedo ekuchongeni iintlobo zeklinikhi. Phakathi kwabo, uhlobo lwe-epidermaal lukhaphukhaphu phantsi kokukhanya kwenkuni; Uhlobo lwe-Dermal lukhanyise i-grey okanye ukukhanya oluhlaza okwesibhakabhaka phantsi kweliso eliphakathi, kwaye umahluko akacacanga phantsi kokukhanya kwenkuni. Ukuhlelwa ngokuchanekileyo kwe-melasma kuyingenelo ekukhetheni unyango kamva.