Indlela entsha yonyango lwe-rosacea kusetyenziswa iteknoloji ye-pulse efanelekileyo: Izifundo ze-In vivo kunye neklinikhi

Imvelaphi:I-Rosacea sisifo solusu esingapheliyo esichaphazela ubuso, kwaye isiphumo sonyango lwangoku asanelisi. Ngokusekelwe kwi-photomodulation ye-optimal pulse technology (OPT), siphuhlise indlela entsha yonyango, oko kukuthi, i-OPT ephucukileyo enamandla aphantsi, ii-pulses ezintathu, kunye nobubanzi be-pulse obude (AOPT-LTL).

Iinjongo:Sijonge ukuphonononga ukuba kunokwenzeka na kunye neendlela ezisisiseko zemolekyuli zonyango lwe-AOPT-LTL kwimodeli yegundane efana ne-rosacea. Ngaphezu koko, sivavanye ukhuseleko kunye nokusebenza kakuhle kwizigulane ezine-erythematotelangiectatic rosacea (ETR).

Impahla nenkqubo:Uhlalutyo lwe-morphological, histological, kunye ne-immunohistochemical lusetyenzisiwe ukuphanda ukusebenza kakuhle kunye neendlela zonyango lwe-AOPT-LTL kwimodeli yegundane efana ne-LL-37-induced rosacea. Ngaphezu koko, izigulane ezingama-23 ezine-ETR zabandakanywa kwaye zafumana amaxesha ahlukeneyo onyango ngamaxesha ahlukeneyo eeveki ezi-2 ngokuxhomekeke kubukhali bemeko yazo. Isiphumo sonyango sivavanywe ngokuthelekisa iifoto zeklinikhi ekuqaleni, iveki e-1, kunye neenyanga ezi-3 emva konyango, kudityaniswe nexabiso elibomvu, amanqaku e-GFSS, kunye ne-CEA.

Iziphumo:Emva konyango lwe-AOPT-LTL lweempuku, siqaphele ukuba i-phenotype efana ne-rosacea, ukungena kweeseli ezivuthayo, kunye nokuphazamiseka kwemithambo yegazi kuye kwaphucuka kakhulu, kwaye ukubonakaliswa kweemolekyuli eziphambili ze-rosacea kuthintelwe kakhulu. Kwisifundo seklinikhi, unyango lwe-AOPT-LTL lube nemiphumo eyanelisayo yonyango kwi-erythema kunye nokuhlanjwa kwezigulane ze-ETR. Akukho ziganeko zimbi zibalulekileyo ezibonwe.

Izigqibo:I-AOPT-LTL yindlela ekhuselekileyo nesebenzayo yokunyanga i-ETR.