Ukwaluphala Kolusu ——Ukhathalelo Lolusu

I-hormone iyancipha ngokukhula, kuquka i-estrogen, i-testosterone, i-dehydroepiandrosterone sulfate, kunye ne-growth hormone. Iziphumo ze-hormones eluswini zininzi, kuquka ukwanda komxholo we-collagen, ukwanda kobukhulu besikhumba, kunye nokuphuculwa komswakama wesikhumba. Phakathi kwazo, impembelelo ye-estrogen icacile ngakumbi, kodwa indlela esebenza ngayo impembelelo yayo kwiiseli ayikaqondwa kakuhle. Impembelelo ye-estrogen eluswini ibonwa kakhulu ngee-keratinocytes ze-epidermis, ii-fibroblasts kunye nee-melanocytes ze-dermis, kunye neeseli ze-hair follicle kunye nee-sebaceous glands. Xa amandla abasetyhini okuvelisa i-estrogen ehla, inkqubo yokwaluphala kwesikhumba iyakhawuleza. Ukunqongophala kwe-hormone estradiol kunciphisa umsebenzi we-basal layer ye-epidermis kwaye kunciphisa ukwenziwa kwe-collagen kunye nee-elastic fibers, zonke ezi zinto zibalulekileyo ekugcineni ukuqina kwesikhumba okuhle. Ukwehla kwamanqanaba e-estrogen emva kokuya exesheni akupheleli nje ekuncipheni komxholo we-collagen yesikhumba, kodwa kunye ne-metabolism yeeseli zesikhumba ichaphazeleka ngamanqanaba e-estrogen aphantsi emva kokuya exesheni, kwaye olu tshintsho lunokuguqulwa ngokukhawuleza ngokusetyenziswa kwe-estrogen ngaphandle kwengxaki. Uvavanyo luqinisekisile ukuba i-estrogen yabasetyhini inokunyusa i-collagen, igcine ulusu lujiyile, kwaye igcine umswakama wesikhumba kunye nomsebenzi wokuthintela i-stratum corneum ngokwandisa i-acidic glycosaminoglycans kunye ne-hyaluronic acid, ukuze ulusu lugcine ukuqina okuhle. Kuyabonakala ukuba ukwehla komsebenzi wenkqubo ye-endocrine yomzimba kukwayenye yezona zinto zibalulekileyo ezichaphazela indlela yokwaluphala kwesikhumba.

Ukuncipha kokukhutshwa kwe-pituitary, adrenal, kunye ne-gonads kunegalelo kutshintsho olubonakalayo kwi-phenotype yomzimba kunye nolusu kunye neendlela zokuziphatha ezinxulumene nokwaluphala. Amanqanaba e-serum ye-17β-estradiol, i-dehydroepiandrosterone, i-progesterone, i-growth hormone, kunye ne-downstream insulin growth factor (IGF)-I hormone yabo yehla ngokukhula. Nangona kunjalo, amanqanaba e-growth hormone kunye ne-IGF-I kwi-serum yamadoda yehla kakhulu, kwaye ukwehla kwamanqanaba e-hormone kwamanye amaqela kunokwenzeka kwinqanaba lobudala. Ii-hormone zinokuchaphazela imo kunye nokusebenza kolusu, ukungena kolusu, ukuphiliswa, i-cortical lipogenesis, kunye ne-metabolism yolusu. Unyango lokutshintshwa kwe-estrogen lunokuthintela ukuyeka ukuya exesheni kunye nokwaluphala kolusu oluvela emvelweni.

——”I-Skin Epiphysiology” Yinmao Dong, Laiji Ma, iChemical Industry Press

Ngoko ke, njengoko sikhula, ingqalelo yethu kwiimeko zolusu kufuneka inyuke kancinci kancinci. Singasebenzisa iingcali ezithileizixhobo zokuhlalutya ulusuukujonga nokuqikelela inqanaba lolusu, ukuqikelela iingxaki zolusu kwangethuba, kunye nokujongana nazo ngenkuthalo.