Amacebiso Okunyamekela Ulusu——Izinto Ezichaphazela Ukuthamba Kolusu

I-elastin yomntu yenziwa ikakhulu ukusuka kwi-embryonic kade ukuya kwixesha lokuzala, kwaye phantse akukho elastin entsha iveliswayo xa umntu emdala. Iintsinga ze-elastic zifumana utshintsho olwahlukileyo ngexesha lokuguga okungapheliyo kunye ne-photoaging.

1. Isini kunye namalungu omzimba ahlukeneyo

Kwangowe-1990, abanye abaphengululi bavavanya amatsha-ntliziyo angama-33 ukuze bahlolisise ukuthamba kolusu kumalungu ali-11 omzimba womntu.

Ibonisa ukuba ukunwebeka kwesikhumba kwahluke kakhulu phakathi kwamalungu ahlukeneyo; ngelixa kungekho mahluko ubalulekileyo phakathi kwezini ezahlukeneyo

Ukunwebeka kwesikhumba ngokuthe ngcembe kuncipha ngokukhula.

2. Ubudala

Ngobudala obukhulayo, ulusu lokuguga olungapheliyo luncinci kwaye luthambile kunesikhumba esincinci, kunye ne-elastic fiber network iyaphuka kwaye iyancipha, ibonakalisa njenge-flatning yesikhumba kunye nemibimbi emihle; ekugugeni okungapheliyo, kungekuphela nje i-fibrous Degradation yamacandelo e-ECM, kodwa kunye nokulahlekelwa kwezinye iinqununu ze-oligosaccharide. I-LTBP-2, i-LTBP-3, kunye ne-LOXL-1 zonke zazilawulwa phezulu, kwaye i-LTBP-2 kunye ne-LOXL-1 idlala indima ebalulekileyo ekulawuleni nasekugcineni i-fibrin deposition, indibano, kunye nesakhiwo ngokubopha i-fibulin-5. Iziphazamiso ezinxulumene nokuchazwa kwezinto zivela njengeendlela zokwandisa ukuguga okungapheliyo.

3. Imiba yokusingqongileyo

Umonakalo wezinto zokusingqongileyo eluswini, ikakhulu ukufota, ukungcoliseka komoya kunye nezinye izinto ziye zahoywa ngokuthe ngcembe, kodwa iziphumo zophando azicwangciswanga.

Ulusu lwe-Photoaging lubonakaliswa yi-catabolic kunye ne-anabolic remodeling kunye nokuguqulwa. Ulusu lubonakala lurhabaxa kwaye lushwabene ngokunzulu ngenxa yokuba kungekuphela nje ilahleko ye-fibrillin-rich-rich fibrils kwi-epidermis-dermal junction, ukuwohloka kwe-elastin, kodwa okona kubaluleke kakhulu, ekubekeni izinto ezinesiphithiphithi se-elastin kwidermis enzulu, umsebenzi we-elastin ochaphazelekayo.

Umonakalo wesakhiwo kwimicu ye-elastic yesikhumba ayinakuguqulwa ngaphambi kweminyaka eyi-18, kwaye ukukhuselwa kwe-UV kubalulekile ngexesha lesigaba sokukhula. Kusenokubakho iindlela ezimbini zokukhanya kwe-elastic fiber sun: i-elastic fibers ithotywa yi-elastase efihliweyo ngamaseli ajikelezayo okanye i-irradiated yi-UV, kunye ne-elastic fibers igobile ngexesha lenkqubo yokudibanisa; iifibroblasts zinefuthe lokukhuthaza iifiber elastic ukugcina umgca. Umphumo uba buthathaka, nto leyo ephumela ekugobeni.— Yinmou Dong Ishishini lemichiza Press, 158-160

Inkqubo yokutshintsha ukuqina kwesikhumba isenokungabonakali ngokwaneleyo kwiliso lenyama, kwaye sinokusebenzisa ubuchwepheshaulusu diagnostic analyzerjonga kwaye uqikelele ikamva lokutshintsha kolusu.

Umzekelo,ISEMECO or Resur Skin Analyzer, ngoncedo lokukhanyisa kobuchwephesha kunye nekhamera ephezulu-definition yokufunda ulwazi lwesikhumba, oludityaniswe ne-AI yokuhlalutya i-algorithm, inokugcina iinkcukacha kunye nokubikezelwa kweenguqu zesikhumba.