Indlela yokuxinana ye-squalene ilele ekubeni ixesha lawo eliphantsi lolungelelwano linokunikela okanye lifumane ii-elektroni ngaphandle kokwenzakalisa i-chain yendlela ye-hydroperoxidey kwindlela ye-hipidy. Izifundo zibonakalise ukuba i-Peroxidation ye-sebum ibangelwa yioksijini yeoksijini, kunye nenqanaba le-oxynin yeoksijini yeoksijini rhoqo kwi-squalene kwi-squum inkulu kunezinye ii-lipids kwisikhumba somntu. Ukupheliswa rhoqo. Nangona kunjalo, kufuneka kuqatshelwe ukuba nangona i-squalene ingasithintela i-lipid perxidation, iimveliso zeqela le-squalene, njengamafutha angenasifo, ikwanefuthe elicaphukisayo kulusu.
I-squalene peroxide inokudlala indima enkulu kwi-pathogenesis ye-acne. Kwimodeli yovavanyo lwezilwanyana, sele kusekiwe ukuba i-squalene monoperoxide inamandla, kwaye umxholo we-squalene peroxide ngokuthe ngcembe inyuka phantsi kwe-iv iarradiation ye-UV. Ke ngoko, kucetyiswa ukuba abaguli be-acne banikele ingqalelo kukhuselo lwelanga, kwayens zinokuphepha i-squalene peroxidation kwimidlalo ye-iltraviolet.
Uhlalutyo lolusuinokusetyenziselwa ukufumana isiphumo se-cream yelanga. Umfanekiso we-UV uboniswe eluhlaza okwesibhakabhaka ukuba kufakwe isicelo seSkyuli yeSkyuli; Ukuba i-Scancreen esemzimbeni isetyenziswa, umfanekiso uyabonakala, ufanayo nentsalela ye-fluorescent.
IXESHA LOKUQALA: APR-29-2022
