Eyona nto iphambili ekwaluphaleni kolusu:
imitha ye-UV, ukufota
I-70% yokwaluphala kolusu ivela kwi-photoaging
Imitha ye-UV ichaphazela i-collagen emzimbeni wethu, nto leyo egcina ulusu lubonakala luselula. Ukuba i-collagen iyancipha, ulusu luya kuba nokuncipha kokuguquguquka, ukugoba, ukufiphala, umbala wolusu ongalinganiyo, i-hyperpigmentation, i-pigmentation kunye nezinye iingxaki zolusu.
I-spectrum ebanzi yelanga yahlulwe yaba yi-UVA kunye ne-UVB. I-UVB ray ine-wavelengths ezimfutshane kwaye ingatshisa kuphela umaleko ophezulu wolusu lwethu, ayikwazi ukungena nzulu eluswini; nangona kunjalo, i-UVA ray ine-wavelengths ezinde kwaye ingangena ngeglasi ize ingene nzulu eluswini, ekugqibeleni iyenza buthathaka i-collagen kwaye ikhokelele ekuphuhlisweni kwemibimbi.
Ngamafutshane, i-UVA ikhokelela ekwaluphaleni, i-UVB ikhokelela ekutshiseni, kwaye ukukhanya kwe-ultraviolet kunokonakalisa i-DNA yeseli, kunciphise umsebenzi we-fibroblast, kwaye ukwenziwa kwe-collagen kuyavalwa, okukhokelela ekuguqukeni kweeseli, ekwaluphaleni, kunye ne-apoptosis. Ngoko ke, i-UV ikhona kuyo yonke indawo, nokuba lilanga okanye lifumile, kufuneka wenze umsebenzi olungileyo wokukhusela ilanga.
Into yesibini ebaluleke kakhulu ekwaluphaleni kolusu
Ii-radicals zasimahla ze-oxidative
Igama eliphambili le-free radicals 'yi-oxygen'. Siphefumla malunga ne-98 ukuya kwi-99% ye-oxygen rhoqo xa siphefumla; isetyenziselwa ukutshisa ukutya esikutyayo nokukhupha iimolekyuli ezincinci ukuze iiseli zethu zikwazi ukunyibilika, kwaye ikhupha amandla amaninzi ukwenza izihlunu zethu zisebenze.
Kodwa mhlawumbi i-1% okanye i-2% yeoksijini ikhetha indlela eyahlukileyo neyingozi, le nxalenye incinci yeoksijini, edla ngokubizwa ngokuba zii-free radicals, ezihlasela iiseli zethu. Ngokuhamba kwexesha, lo monakalo uyaqokelelana ngokuhamba kwexesha.
Ezona zibonakalayo ziimpawu zokwaluphala ezibonakala eluswini. Umzimba wethu unendlela yokuzikhusela elungisa umonakalo owenziwe kwiiseli zethu zii-free radicals, kodwa xa ii-free radicals ziqokelelana ngokukhawuleza kunokuba iiseli zomzimba zinokuzilungisa, ulusu luyaguga kancinci kancinci.
Umfanekiso ongasentla sisicwili sokwenyani somzimba wethu, ungabona ngokucacileyo ukuba i-epidermis ephezulu imnyama kwaye i-dermis esezantsi ikhanya kancinci, i-dermis kulapho sivelisa khona i-collagen, kwaye iiseli ezivelisa i-collagen zibizwa ngokuba yi-fibroblasts, eziziimashini zokwenza i-collagen.
Iifibroblast ezisembindini womfanekiso ziifibroblast, kwaye i-spider web ezijikelezileyo yi-collagen. I-Collagen iveliswa zii-fibroblast, kwaye ulusu oluselula luyinethiwekhi ye-collagen enamacala amathathu kwaye idityaniswe ngokuqinileyo, apho ii-fibroblast zitsala ngamandla iifayibha ze-collagen ukuze zinike ulusu oluselula ubume obupheleleyo nobuthambileyo.
Kwaye ulusu oludala, ii-fibroblast kunye nekhonkco le-collagen phakathi kokuqhekeka kwee-fibroblast ezigugayo zihlala zingavumi ukungena kwe-collagen, ngokuhamba kwexesha, ulusu nalo lwaqala ukuguga, yile nto sihlala siyithetha ukuguga kolusu, sisombulula njani i-oxidation yolusu olufunyenweyo?
Ukongeza ekunikeleni ingqalelo engakumbi kwi-sunscreen, singasebenzisa ezinye kunye ne-vitamin A, i-vitamin E, i-ferulic acid, i-resveratrol kunye nezinye izithako zeemveliso zokhathalelo lolusu; ngokuqhelekileyo sinokutya iziqhamo kunye nemifuno enemibala eqaqambileyo, njengeetumato, iitumato zityebile kwi-lycopene.
Ingafunxa kakuhle ioksijini kwaye ithintele uxinzelelo lwe-oxidative, ungatya nebroccoli engakumbi, ibroccoli inenxalenye ebizwa ngokuba yi-mustard oil glycosides, emva kokuthatha esi sithako, iya kugcinwa eluswini, ukuze iiseli zesikhumba zikwazi ukuzikhusela, ezi ziqhamo kunye nemifuno zinokukhuthaza ukumelana kweeseli nokwaluphala.
Into yesithathu ebaluleke kakhulu ekwaluphaleni kolusu
Ukulungiswa kolusu
I-Glycation, ngokweengcali, ibizwa ngokuba yi-non-enzyme glycosylation reaction okanye i-Melad reaction. Umgaqo kukuba ukunciphisa iiswekile kubopha kwiiproteni xa kungekho enzymes; ukunciphisa iiswekile kuguqulwa kakhulu ngeeproteni, kwaye ukunciphisa iiswekile kunye neeproteni kulandela i-oxidation ende, i-dehydrogenation, kunye ne-rearrangement reaction, nto leyo ekhokelela ekuvelisweni kweemveliso ze-glycosylation ezikwinqanaba lokugqibela, okanye ii-AGEs ngamafutshane.
I-AGEs liqela lenkunkuma yezinto eziphilayo ezingenakulungiseka, ezimthubi-mdaka, ezihambelanayo nezingoyikiyo ukutshatyalaliswa kwee-enzyme, kwaye zezinye zezona zinto ziphambili zokwaluphala kwabantu. Njengoko sikhula, i-AGEs iqokelelana emzimbeni, nto leyo ekhokelela ekwandeni kobunzima beendonga zangaphakathi zemithambo yegazi, ukungalingani kwindlela umzimba osebenza ngayo amathambo okukhokelela kwi-osteoporosis, kunye nokutshatyalaliswa kweefayibha ze-collagen kunye ne-elastin kwi-dermis okukhokelela ekwaluphaleni kwesikhumba. Ukwaluphala kwesikhumba okubangelwa yi-glycation kushwankathelwe kwisivakalisi esinye: iswekile itshabalalisa iiproteni ezisempilweni kwaye iguqula izakhiwo zeproteni eziselula zibe zizakhiwo zeproteni ezindala, nto leyo ekhokelela ekwaluphaleni nasekulahlekelweni kokuqina kwe-collagen kunye neefayibha ze-elastic kwi-dermis.
Ixesha leposi: Meyi-29-2024
